Saturday talks

Talk synopsis & speaker profile



12:30 UNTIL 12:55

Cambridge Rare Disease Network - RAREfest | Speaker - Dr Delphine Larrieu 1

Dr DelphIne Larrieu

Can we turn back the clock on progeria – rare premature ageing diseases?

Talk synopsis: Premature ageing syndromes called progeria are due to dysfunction in the cell nucleus structure. This triggers the appearance of ageing signs in early childhood, cardiovascular dysfunction and premature death around 14 years old. Unfortunately, there is no current cure for these diseases and the available therapies mainly act by improving the symptoms of these patients. Delphine will discuss how her team is tackling this by characterizing new mechanisms that regulate cell nucleus function in progeria, suggesting new ways of treating these diseases. The lab’s work could also open up new perspectives into improving normal age-related pathologies.

Bio: Dr Delphine Larrieu completed her PhD in 2010 at the University of Grenoble, France. She then undertook her postdoctoral training with Professor Steve Jackson at the University of Cambridge, with independent funding from EMBO and from the Medical Research Council. She then obtained a Sir Henry Dale Wellcome Trust fellowship, allowing her to set up her own lab at the Cambridge Institute for Medical Research.

Delphine’s lab is interested in understanding mechanisms driving rare premature ageing syndromes called progeria, and in identifying new ways to treat these diseases.

Click to visit Delphine’s webpage.

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